4/19/2023 0 Comments Corm orn gordThese findings support the importance of oxytocin for enhancing positive behavioral and neural responses to social touch in the form of manually administered massage and that a combination of intranasal oxytocin and massage may have therapeutic potential in autism.Ĭlinical Trials Registration: The Effects of Oxytocin on Social Touch registration ID: NCT03278860 URL. Both neural and behavioral effects of oxytocin occurred independent of whether subjects thought the massage was applied by a male or female masseur. Intranasal oxytocin significantly increased subjective pleasantness ratings of the manual but not the machine massage and neural responses in key regions involved in reward (orbitofrontal cortex, dorsal striatum and ventral tegmental area), social cognition (superior temporal sulcus and inferior parietal lobule), emotion and salience (amygdala and anterior cingulate and insula) and default mode networks (medial prefrontal cortex, parahippocampal gyrus, posterior cingulate, and precuneus) as well as a number of sensory and motor processing regions. 46 male participants underwent blocks of massage of each type where they both received and imagined receiving the massage. In the present study, we investigated whether intranasal oxytocin modulates behavioral and neural responses to foot massage applied manually or by machine using a randomized placebo-controlled within-subject pharmaco-fMRI design. Manually-administered massage can potently increase endogenous oxytocin concentrations and neural activity in social cognition and reward regions and intranasal oxytocin can increase the pleasantness of social touch. ![]() 2Department of Molecular Psychology, Institute of Psychology and Education, Ulm University, Ulm, Germany.1The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for NeuroInformation, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu, China.Sent to: Hennepin Healthcare Foundation, 701 Park Ave.Yuanshu Chen 1, Qin Li 1, Qianqian Zhang 1, Juan Kou 1, Yingying Zhang 1, Han Cui 1, Jennifer Wernicke 2, Christian Montag 1,2, Benjamin Becker 1, Keith M. Payable to: Hennepin Healthcare Foundation Make an online donation by writing Hitchcock in the 'other' line of our transaction form. Tax-deductible charitable investments help us to shape these young, committed individuals into fine surgeons who can contribute beyond their technical skills. The challenging patient base that shapes our surgeons also provides a rich data mine from which residents build research, in keeping with the Society's goals of improving the practice, elevating the standards, and advancing the science of surgery. Those selected to enter the surgical residency are passionate about caring for an underserved and culturally diverse patient base and have already proven themselves as outstanding among their peers. Hennepin Healthcare's Surgical Residency Program is highly sought each year with over 400 applicants vying for five spots in a five-year program that will shape them into surgeons and researchers, and on to fellowships, private practice, or public medicine.
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